TOP CONOLIDINE ALKALOID FOR CHRONIC PAIN SECRETS

Most recently, it's been identified that conolidine and the above mentioned derivatives act to the atypical chemokine receptor 3 (ACKR3. Expressed in identical regions as classical opioid receptors, it binds to the wide array of endogenous opioids. Contrary to most opioid receptors, this receptor acts for a scavenger and does not activate a second